KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MKNK1
All Species:
4.55
Human Site:
S192
Identified Species:
9.09
UniProt:
Q9BUB5
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BUB5
NP_001129025.1
465
51342
S192
A
P
T
S
L
G
S
S
D
P
P
T
S
A
S
Chimpanzee
Pan troglodytes
XP_001162271
453
49967
S180
A
P
T
S
L
G
S
S
D
P
P
T
S
A
S
Rhesus Macaque
Macaca mulatta
XP_001098645
414
46209
K171
I
L
C
E
S
P
E
K
V
S
P
V
K
I
C
Dog
Lupus familis
XP_539626
415
46182
V172
L
C
E
S
P
E
K
V
S
P
V
K
I
C
D
Cat
Felis silvestris
Mouse
Mus musculus
O08605
427
47896
P181
E
N
I
L
C
E
S
P
E
K
V
S
P
V
K
Rat
Rattus norvegicus
Q4G050
413
46195
P169
E
N
I
L
C
E
S
P
E
K
V
S
P
V
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001235171
508
56331
F225
H
I
Q
K
R
K
H
F
N
E
R
E
A
S
K
Frog
Xenopus laevis
Q9YGW0
418
46898
V175
F
K
D
K
V
S
P
V
K
I
C
D
F
D
L
Zebra Danio
Brachydanio rerio
NP_001108211
459
51123
V198
E
R
E
A
S
R
V
V
R
D
I
A
N
A
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651986
1142
128445
F261
C
P
I
K
I
C
D
F
D
L
G
S
G
I
K
Honey Bee
Apis mellifera
XP_395927
516
58135
F199
T
P
I
K
V
C
D
F
D
L
G
S
G
I
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_779905
511
56921
F258
S
P
I
K
I
C
D
F
G
L
G
S
G
I
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.7
87.9
82.8
N.A.
85.3
82.3
N.A.
N.A.
51.5
72
68.3
N.A.
20.3
46.1
N.A.
37.7
Protein Similarity:
100
96.7
88.1
85.8
N.A.
88.5
85.3
N.A.
N.A.
63.3
79.7
76.7
N.A.
28.2
63.1
N.A.
52.4
P-Site Identity:
100
100
6.6
13.3
N.A.
6.6
6.6
N.A.
N.A.
0
0
6.6
N.A.
13.3
13.3
N.A.
6.6
P-Site Similarity:
100
100
6.6
13.3
N.A.
20
20
N.A.
N.A.
20
6.6
20
N.A.
26.6
26.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
0
0
9
0
0
0
0
0
0
0
9
9
25
0
% A
% Cys:
9
9
9
0
17
25
0
0
0
0
9
0
0
9
9
% C
% Asp:
0
0
9
0
0
0
25
0
34
9
0
9
0
9
9
% D
% Glu:
25
0
17
9
0
25
9
0
17
9
0
9
0
0
0
% E
% Phe:
9
0
0
0
0
0
0
34
0
0
0
0
9
0
0
% F
% Gly:
0
0
0
0
0
17
0
0
9
0
25
0
25
0
0
% G
% His:
9
0
0
0
0
0
9
0
0
0
0
0
0
0
9
% H
% Ile:
9
9
42
0
17
0
0
0
0
9
9
0
9
34
0
% I
% Lys:
0
9
0
42
0
9
9
9
9
17
0
9
9
0
42
% K
% Leu:
9
9
0
17
17
0
0
0
0
25
0
0
0
0
17
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
17
0
0
0
0
0
0
9
0
0
0
9
0
0
% N
% Pro:
0
42
0
0
9
9
9
17
0
25
25
0
17
0
0
% P
% Gln:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
9
0
0
9
9
0
0
9
0
9
0
0
0
0
% R
% Ser:
9
0
0
25
17
9
34
17
9
9
0
42
17
9
17
% S
% Thr:
9
0
17
0
0
0
0
0
0
0
0
17
0
0
0
% T
% Val:
0
0
0
0
17
0
9
25
9
0
25
9
0
17
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _